RECENT PUBLICATIONS

CELLULAR AND MOLECULAR PATHOBIOLOGY OF HEART FAILURE WITH PRESERVED EJECTION FRACTION

Jan 2021 Nature Reviews Cardiology

REDUCED RIGHT VENTRICULAR SARCOMERE CONTRACTILITY IN HFPEF WITH SEVERE OBESITY

Dec 2020 Circulation

MYOCARDIAL GENE EXPRESSION SIGNATURES IN HUMAN HEART FAILURE WITH PRESERVED EJECTION FRACTION

Oct 2020 Circulation

CHIP PHOSPHORYLATION BY PROTEIN KINASE G ENHANCES PROTEIN QUALITY CONTROL AND ATTENUATES CARDIAC ISCHEMIC INJURY

Oct 2020 Nat Comm

RECENT HFPEF WORK

October 2020

TARGETING PROTEIN KINASE G TO TREAT CARDIAC PROTEOTOXICITY

July 2020 Front Physiol

PKG1Α CYSTEINE-42 REDOX STATE CONTROLS MTORC1 ACTIVATION IN PATHOLOGICAL CARDIAC HYPERTROPHY

July 2020 Circ Res

ENDOMYOCARDIAL BIOPSY CHARACTERIZATION OF HEART FAILURE WITH PRESERVED EJECTION FRACTION AND PREVALENCE OF CARDIAC AMYLOIDOSIS

July 2020 JACC Heart Failure

OBESITY COULD SHIFT SEVERE COVID-19 DISEASE TO YOUNGER AGES

May 2020 Lancet

LEVERAGING SIGNALING PATHWAYS TO TREAT HEART FAILURE WITH REDUCED EJECTION FRACTION.

May 2019 Circ Res

IN VIVO SELECTIVE INHIBITION OF TRPC6 BY ANTAGONIST BI 749327 AMELIORATES FIBROSIS AND DYSFUNCTION IN CARDIAC AND RENAL DISEASE

April 2019 PNAS

PKG1-MODIFIED TSC2 REGULATES MTORC1 ACTIVITY TO COUNTER ADVERSE CARDIAC STRESS

January 2019 Nature

CHRONIC ATRIAL AND VENTRICULAR PACING IN THE MOUSE

February 2019 Circ Heart Fail

MARKED DISPARITY OF MICRORNA MODULATION BY CGMP-SELECTIVE PDE5 VERSUS PDE9 INHIBITORS IN HEART DISEASE

August 2018 JCI Insight

ACUTE ENHANCEMENT OF CARDIAC FUNCTION BY PHOSPHODIESTERASE TYPE 1 INHIBITION

October 2018 Circulation

TRANSIENT RECEPTOR POTENTIAL CHANNEL 6 REGULATES ABNORMAL CARDIAC S-NITROSYLATION IN DUCHENNE MUSCULAR DYSTROPHY

December 2017 PNAS

NEONATAL TRANSPLANTATION CONFERS MATURATION OF PSC-DERIVED CARDIOMYOCYTES CONDUCIVE TO MODELING CARDIOMYOPATHY

January 2017 Cell Rep

TETRAHYDROBIOPTERIN PROTECTS AGAINST HYPERTROPHIC HEART DISEASE INDEPENDENT OF MYOCARDIAL NITRIC OXIDE SYNTHASE COUPLING

March 2016 J Am Heart Assoc

PACEMAKER-INDUCED TRANSIENT ASYNCHRONY SUPPRESSES HEART FAILURE PROGRESSION.

Dec 2015 Sci Transl Med

DUAL LABELING BIOTIN SWITCH ASSAY TO REDUCE BIAS DERIVED FROM DIFFERENT CYSTEINE SUBPOPULATIONS: A METHOD TO MAXIMIZE S-NITROSYLATION DETECTION

January 25, 2025

PREVENTION OF PKG1Α OXIDATION AUGMENTS CARDIOPROTECTION IN THE STRESSED HEART

June 2015 JCI

PHOSPHODIESTERASE 9A CONTROLS NITRIC-OXIDE-INDEPENDENT CGMP AND HYPERTROPHIC HEART DISEASE

March 2015 Nature

SOLUBLE GUANYLATE CYCLASE IS REQUIRED FOR SYSTEMIC VASODILATION BUT NOT POSITIVE INOTROPY INDUCED BY NITROXYL IN THE MOUSE

February 2015 Hypertension

 

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